Set up VXG as a 4 channel.
Run source alignment wizard to calibrate the four VXG outputs at the ends of the cables using an oscilloscope.
Connect VNA reference out to VXG reference in.
For IQ upconverter:
Coonect the VXG source outputs to the DUT balanced I/Q inputs.
Connect the DUT RF output to VNA port 1.
Connect the DUT LO input to VNA port 3.

Set up VXG as an external source.
Define VXG as a multi-channel source.
Enable output synchronization of VXG.
Disable the checkbox "Allow VNA to Preset Source (Recommended)"
Enable DIQ application
Define the four VXG outputs as phase-controlled outputs
Define VNA port 1 as the measured input
Define VNA port 3 as a fixed frequency LO signal.
Calibrate port 1 and port 3.